The Impact Of Extreme Physical Exertion On Salivary Anti-Microbial Protein Responses, Circulatory Endotoxin Concentrations And Cytokine Profile: Do Probiotics Have A Role To Play?


Gill, S. (2016) The Impact Of Extreme Physical Exertion On Salivary Anti-Microbial Protein Responses, Circulatory Endotoxin Concentrations And Cytokine Profile: Do Probiotics Have A Role To Play?. Unpublished PhD Thesis. Coventry: Coventry University


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Abstract

Extreme physical exertion is commonly associated with acute physiological changes in immune variables known to disturb host defences. Likely induced by the production of stress hormones (e.g., cortisol), partaking in ultra-endurance events with accompanying physiological stressors ((e.g., environmental extremes, sleep deprivation and compromised hydration and (or) nutritional status)) may amplify stress hormone responses and compromise immune status to a greater extent. To date, research investigating the impact of extreme physical exertion (e.g., ultra-marathon events) on physiological variables is extremely limited. More recently, the potential use of probiotics with known immunomodulatory effects may be considered an appropriate nutritional strategy to improve host defences and minimise and (or) prevent sub-clinical or clinically significant outcomes in active populations.



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Item TypeThesis (PhD)
Title The Impact Of Extreme Physical Exertion On Salivary Anti-Microbial Protein Responses, Circulatory Endotoxin Concentrations And Cytokine Profile: Do Probiotics Have A Role To Play?
Authors Gill, S.
Uncontrolled KeywordsExertion, Running, Endurance, Probiotics
Departments Faculty of Health and Life Sciences
Centre for Applied Biological and Exercise Sciences (ABES)
Publisher statementSome materials have been removed from this thesis due to third party copyright. Pages where material has been removed are clearly marked in the electronic version. The unabridged version of the thesis can be viewed at the Lanchester Library, Coventry University.
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Deposited on 14-Dec-2016 in Research - Coventry.
Last modified on 14-Dec-2016

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